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Please use this identifier to cite or link to this item: https://rep.polessu.by/handle/123456789/31784
Title: Роль супероксидного радикала в реализации активаторной функции стрептокиназы
Authors: Никандров, В.Н.
Пыжова, Н.С.
Вотяков, В.И.
Клингер, Ю.Е.
Keywords: стрептокиназа
плазминоген
Issue Date: 1987
Citation: Роль супероксидного радикала в реализации активаторной функции стрептокиназы / В.Н. Никандров, Н.С. Пыжова, В.И. Вотяков, Ю.Е. Клингер // Доклады Академии наук БССР. – 1987. – Том 31, № 4. – С. 375-378.
Abstract: The scavengers of superoxide radicals, nitro blue tetrazolium or adrenaline at final concentrations of 5*10- 3 —10- 2 M inhibit the activating function of streptokinase. The addition of the complexing agents (8-hydroxyquinoline, sodium diethyldithiocarbamate, o-phenanthroline and EDTA) to streptokinase solution changes its activating function depending on the type of the agent and the conformational state of the protein molecule. It is concluded that superoxide radicals participate in the activating function of streptokinase and metals with variable valence are present in its molecule.
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