Please use this identifier to cite or link to this item: https://rep.polessu.by/handle/123456789/31838
Title: Влияние адениловых нуклеотидов на активаторную функцию стрептокиназы
Other Titles: Influence of adenylic nucleotides on the activating function of streptokinase
Authors: Никандров, В.Н.
Пыжова, Н.С.
Вотяков, В.И.
Nikandrov, V.N.
Pyzhova, N.S.
Votyakov, V.I.
Keywords: стрептокиназ
фибрино­лиз
адениловые нуклеотиды
Issue Date: 1987
Citation: Никандров, В.Н. Влияние адениловых нуклеотидов на активаторную функцию стрептокиназы / В.Н. Никандров, Н.С. Пыжова, В.И. Вотяков // Бюллетень экспериментальной биологии и медицины. – 1987. – Т. 104, № 7. – С. 49-51.
Description: The addition of ATP or 3,5-AMP (but not UTP, GTP, CTP, AMP, 2,3-AMP, ADP, inorganic pyrophosphate) at a final concentration of 10 - 1 M into streptokinase solution, pH 7.0 or 9.5, causes a dramatical inhibition of streptokinase-induced fibrinolysis. The specificity of ATP effect is fully lost at pH 3.0, when all nucleotides completely inhibit the activating function of streptokinase. Ribose-5-phosphate causes a similar effect at pH 3.0. The character of nucleotide action on the activating function of streptokinase considerably differs from their influence on proteolytic reactions.
Appears in Collections:Публикации сотрудников / Publications of the teaching stuff of Polessky State University

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