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Title: | Влияние адениловых нуклеотидов на активаторную функцию стрептокиназы |
Other Titles: | Influence of adenylic nucleotides on the activating function of streptokinase |
Authors: | Никандров, В.Н. Пыжова, Н.С. Вотяков, В.И. Nikandrov, V.N. Pyzhova, N.S. Votyakov, V.I. |
Keywords: | стрептокиназ фибринолиз адениловые нуклеотиды |
Issue Date: | 1987 |
Citation: | Никандров, В.Н. Влияние адениловых нуклеотидов на активаторную функцию стрептокиназы / В.Н. Никандров, Н.С. Пыжова, В.И. Вотяков // Бюллетень экспериментальной биологии и медицины. – 1987. – Т. 104, № 7. – С. 49-51. |
Description: | The addition of ATP or 3,5-AMP (but not UTP, GTP, CTP, AMP, 2,3-AMP, ADP, inorganic pyrophosphate) at a final concentration of 10 - 1 M into streptokinase solution, pH 7.0 or 9.5, causes a dramatical inhibition of streptokinase-induced fibrinolysis. The specificity of ATP effect is fully lost at pH 3.0, when all nucleotides completely inhibit the activating function of streptokinase. Ribose-5-phosphate causes a similar effect at pH 3.0. The character of nucleotide action on the activating function of streptokinase considerably differs from their influence on proteolytic reactions. |
Appears in Collections: | Публикации сотрудников / Publications of the teaching stuff of Polessky State University |
Files in This Item:
File | Description | Size | Format | |
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Vliianie_adenilovykh.pdf | 6.61 MB | Adobe PDF | View/Open |
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