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Title: | Determination of ambroxol hydrochloride concentration in the air of pharmaceutical production by spectrophotometric method |
Authors: | Krymskaya, T.P. Lebedinskaya, K.S. Sharamkov, I.V. Lemiasheuski, V.O. |
Keywords: | ambroxol hydrochloride spectrophotometry determination methodology working zone |
Issue Date: | 2023 |
Publisher: | Minsk |
Citation: | Determination of ambroxol hydrochloride concentration in the air of pharmaceutical production by spectrophotometric method / T.P. Krymskaya, K.S. Lebedinskaya, I.V. Sharamkov, V.O. Lemiasheuski // Actual Environmental Problems : Proceedings of the XIII International Scientific Conference of young scientists, graduates, master and PhD students, Minsk, Republic of Belarus, November 30 – December 1, 2023 / ISEI BSU; edited by: A. Rodzkin, M. Germenchuk. – Minsk, 2023. – P. 75-76. |
Abstract: | The results of development of the author's spectrophotometric technique for determination of the mass concentration of ambroxol hydrochloride in the air of pharmaceutical enterprises are proposed. It is based on concentration of ambroxol hydrochloride from air on paper filters AFA-VP, its extraction from filters with methanol under the action of ultrasound, concentration of the extract by complete removal of methanol, dissolution of the dry residue in distilled water, derivatisation reactions with 3-methyl-2-benzothiazolinone hydrazone hydrochloride in the presence of ammonium cerium (IV) sulphate and subsequent determination of the reaction product by spectrophotometric method. Quantitative determination is performed by absolute calibration method. |
Appears in Collections: | Публикации сотрудников / Publications of the teaching stuff of Polessky State University |
Files in This Item:
File | Description | Size | Format | |
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Determination.pdf | 485.27 kB | Adobe PDF | View/Open |
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