Please use this identifier to cite or link to this item: https://rep.polessu.by/handle/123456789/28476
Title: Расщепление белковых субстратов внутриклеточными протеиназами Corynebacterium diphtheriae PW-8
Other Titles: Splitting of protein substrates by intracellular proteinases of Corynebacterium diphtheriae PW-8
Authors: Никандров, В.Н.
Пыжова, Н.С.
Шатило, Н.Л.
Nikandrov, V.N.
Pyzhova, N.S.
Shatilo, N.L.
Keywords: протеиназы
фибриноген
Issue Date: 2004
Publisher: Минск : ГУ РНМБ
Citation: Никандров, В.Н. Расщепление белковых субстратов внутриклеточными протеиназами Corynebacterium diphtheriae PW-8 / В.Н. Никандров, Н.С. Пыжова, Н.Л. Шатило // Достижения медицинской науки Беларуси: научно-практ. ежегодник / Респ. науч. мед. б-ка; гл. ред. И.Е. Гурманчук. – Минск : ГУ РНМБ, 2004. – Вып. IХ. – С. 65–66.
Description: Corynebacteium diphtheriae PW-8 (grown in the presence of blood serum) proteinases splits human fibrinogen > human serum albumin = casein > gelat in > human thrombin. Fibrinogenolytic activities of these proteinases were inhibited by the group of specific proteinase inhibitors (0.001 mol) and by o-phenanthroline, by Hg2+ ions (0.001 mol) and stimulated by Fe2+> Fe3+ ions. This activity was inhibited by nitrotetrazolium blue or sodium acid (0.01 mol) completely, and by some purine nucleotides, especially by ATP or GTP. The sensivity of proteinase activity to effectors depended on cultivation conditions (nitrient medium).
Appears in Collections:Публикации сотрудников / Publications of the teaching stuff of Polessky State University

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