Please use this identifier to cite or link to this item: https://rep.polessu.by/handle/123456789/28475
Title: Образование эффекторов протеолиза в культуральной жидкости при росте Corynebacterium diphtheriae
Authors: Никандров, В.Н.
Пыжова, Н.С.
Nikandrov, V.N.
Pyzhova, N.S.
Keywords: протеолиз
плазминоген
токсин
Issue Date: 2004
Publisher: Минск : ГУ РНМБ
Citation: Никандров, В.Н. Образование эффекторов протеолиза в культуральной жидкости при росте Corynebacterium diphtheriae / В.Н. Никандров, Н.С. Пыжова // Достижения медицинской науки Беларуси: научно-практ. ежегодник / Респ. науч. мед. б-ка; гл. ред. И.Е. Гурманчук. – Минск : ГУ РНМБ, 2004. – Вып. IХ. – С. 64-65.
Description: Protein fractions were isolated with trichloroacetic acid treatment of culturtal fluids after corynebacterium PW-8 growth. These fractions inhibited fibrinolytic activity of papain (60-65%), pepsin (50-75%), plasmin (40%) and a-chymotrypsin (20-30%). Isolated fractions increased the plasminogen-activating ability of streptokinase (up to 135-152%), tissue plasminogen activator from swine heart (up to 175-255%) and y-subunit of nerve growth factor (up to 130-150%). At the same time 50-95% of such ability of 0-subunit of nerve growth factor was decreased in the presence of these effectors.
Appears in Collections:Публикации сотрудников / Publications of the teaching stuff of Polessky State University

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