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Title: | Образование эффекторов протеолиза в культуральной жидкости при росте Corynebacterium diphtheriae |
Authors: | Никандров, В.Н. Пыжова, Н.С. Nikandrov, V.N. Pyzhova, N.S. |
Keywords: | протеолиз плазминоген токсин |
Issue Date: | 2004 |
Publisher: | Минск : ГУ РНМБ |
Citation: | Никандров, В.Н. Образование эффекторов протеолиза в культуральной жидкости при росте Corynebacterium diphtheriae / В.Н. Никандров, Н.С. Пыжова // Достижения медицинской науки Беларуси: научно-практ. ежегодник / Респ. науч. мед. б-ка; гл. ред. И.Е. Гурманчук. – Минск : ГУ РНМБ, 2004. – Вып. IХ. – С. 64-65. |
Description: | Protein fractions were isolated with trichloroacetic acid treatment of culturtal fluids after corynebacterium PW-8 growth. These fractions inhibited fibrinolytic activity of papain (60-65%), pepsin (50-75%), plasmin (40%) and a-chymotrypsin (20-30%). Isolated fractions increased the plasminogen-activating ability of streptokinase (up to 135-152%), tissue plasminogen activator from swine heart (up to 175-255%) and y-subunit of nerve growth factor (up to 130-150%). At the same time 50-95% of such ability of 0-subunit of nerve growth factor was decreased in the presence of these effectors. |
Appears in Collections: | Публикации сотрудников / Publications of the teaching stuff of Polessky State University |
Files in This Item:
File | Description | Size | Format | |
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Obrazovanie_effektorov_proteoliza.pdf | 3.74 MB | Adobe PDF | View/Open |
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