Please use this identifier to cite or link to this item: https://rep.polessu.by/handle/123456789/32347
Title: Changes in the ion cur-rents of neurons under the action of local anesthetics
Authors: Mileiko, А.А.
Lemiasheuski, V.O.
Ostrenko, K.S.
Keywords: sodium channels
local anaesthetics
sodium channel blockers
pain relief
Issue Date: 2023
Publisher: Minsk
Citation: Mileiko, А.А. Changes in the ion cur-rents of neurons under the action of local anesthetics / А.А. Mileiko, V.O. Lemiasheuski, K.S. Ostrenko // Actual Environmental Problems: Proceeings of the XIII International Scientific Conference of young scientists, graduates, master and PhD students, Minsk, Republic of Belarus, November 30 – December 1, 2023 / ISEI BSU; edited by: A. Rodzkin, M. Germenchuk. – Minsk, 2023. – P. 41-42.
Abstract: Modern local anesthetics suppress ion currents in excitable membranes by interacting with channels from the cytoplasmic side of the cell membrane. The mechanism of the effect of local anesthetics on the permeability of the functional membrane for sodium and potassium ions has been investigated. The blocking effect of local anesthetics on the permeability of the membrane for ions is shown. A comparative analysis of the intensity and duration of the action of the anesthetic substances studied on the ion flows of Na+ and K+ was carried out.
Appears in Collections:Публикации сотрудников / Publications of the teaching stuff of Polessky State University

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